ANTISTRESS

VISCOUS, OPALESCENT LIQUID FROM LIGHT YELLOW TO YELLOW COLOR, WITH THE ODOR OF MEAT.

COMPOSITION
1 ml of the drug contains the active substance:
• Phenibut – 100 mg.
Excipients: Propylene Glycol, Methyl Paraben, Propyl Paraben, Hydroxyethyl Cellulose, Flavor, Sucrose, Purified Water.



PHARMACOLOGICAL PROPERTIES
• АТС vet QN06BX – Other psychostimulants and nootropics. QN06BX22 – Phenibut.
• Phenibut, as part of the drug, is a phenyl derivative of GABA and Phenylethylamine. It has a positive effect on metabolic processes in the nerve cells of the brain.
• Phenibut exhibits nootropic activity, and as a derivative of GABA has an anxiolytic (tranquilizing) effect. It does not affect choline- and adrenoreceptors. By strengthening inhibitory GABA-ergic processes, affects the functional state due to the normalization of metabolism and effects on cerebral circulation.
• It has a pronounced stress-correcting effect and provides the normalization of the processes of excitation and inhibition in the central nervous system.
• The drug is rapidly absorbed after oral administration and penetrates well into all tissues of the body, including the blood-brain barrier.
• 80-95% of the drug is metabolized in the liver to inactive metabolites. 5% is excreted from the body by the kidneys unchanged.

ADMINISTRATION
The drug Antistress is administered to reduce the excitation and correction of psychogenic behavioral disorders in cats and dogs under stress, phobias, aggression for no apparent reason and with increased sexual arousal (together with contraceptives), for the prevention of motion sickness.

DOSAGE
Drops Antistress are administered to Cats and Dogs orally on the root of the tongue 2 times daily in the following doses:
• Cats:   1 drop of the drug (4 mg of phenibut) per 1 kg of animal body weight;
• Dogs:   2 drops of the drug (8 mg of phenibut) per 1 kg of animal body weight.
• The course of treatment is 10-15 days. If there are signs of severe excitation and psychogenic behavioral disorders (aggression, fear, hyperactivity, hypersexual behavior), the course can be extended up to 20 days.
• With the re-manifestation in animals of signs of excitation and/or behavior disorders, the course of the drug is repeated in the same doses, according to the same schema.
• In order to prevent stress (transportation, change of scenery, pyrotechnics explosions, departure of the owner, participation in exhibitions and competitions), the drug is used 3-5 days before the upcoming event and within 1-4 days after its completion.
• To prevent motion sickness, the drug is used once in the above doses 1-2 hours before a specific start of the transportation of the animal. When expressed signs of motion sickness (vomiting) appear, the drug is not effective.
• To correct behavior with increased sexual activity, drops of Antistress are administered in the same doses, together with contraceptives. The duration of the course depends on the individual sensitivity of the animals and the degree of excitement.

CONTRAINDICATIONS
Individual sensitivity to the components of the drug (including anamnesis), acute and chronic renal failure, and diabetes.
Do not use for pregnant and lactating females.

PRESENTATION
Polymer dropper vials of 10, 30 ml.

STORAGE CONDITIONS
Store in a dark place, out of the reach of children between 5°С to 25°С.
During storage, sediment is possible, which is easily broken when shaken.

SHELF LIFE
12 months. After the first opening of the vial – 28 days, if it is stored in a dark place at a temperature between 5°C to 25°C.