OXYTOCIN

Sterile Solution for Injection

COMPOSITION
1 ml of the drug contains:

Active Ingredients mg/ml
Oxytocin (equivalent to 10 IU Oxytocin) 0,0166
Excipients Solvents q.s 1 ml


TARGET SPECIES
Mare, Cow, Ewe, Goat, Bitch, and Queen.

INDICATIONS
Injections with this product will initiate strong, regular and purposeful contractions of the uterine muscle especially in the later stages of pregnancy and post-partum. It also evokes the “let-down” of milk although it has no action on the smooth muscles of the gut or urinary bladder, nor is it effective in the treatment of Diabetes Insipidus. The absence of vasopressor and antidiuretic effects makes it particularly suitable for obstetric use (stimulation of parturition, promotion of uterine involution and control of post-partum haemorrhage) and the treatment of Agalactia.
- The product is indicated for:
• Stimulation of uterine contraction to facilitate parturition in the presence of a fully dilated cervix.
• To promote involution of the post-parturient uterus and thus aid the passage of retained placenta.
• To aid in the control of post-partum haemorrhage.
• Promotion of milk “let-down” in cases of Agalactia and to facilitate “stripping out” of infected quarters in the treatment of mastitis in Cows.

MODE OF ADMINISTRATION
Administered by deep intramuscular injection (IM) or slow intravenous injection (IV).

Obstetrics

Mare : 4-5 ml per animal by IM.
Cow : 4-5 ml per animal by IM.
Ewe : 1-3 ml per animal by IM.
Goat : 5-15 IU per animal by IM.
Bitch : 0,5-1 IU per animal depending on body weight by IM (administration during delivery) or 0,1-1 ml by IM (administration postpartum).
Queen : 0,3-1 IU per animal depending on body weight by IM (administration during delivery) or 0,1-0,3 ml by IM (administration postpartum).
- During or shortly after delivery the minimum dose should be administered in all large animal species; this dosage can be repeated after approximately 30 minutes. The maximum dosage should be administered when several hours have passed since delivery.
- Where the intravenous route is used, these doses should be reduced to one-quarter of the intramuscular dose and the injection given slowly at a dilution of ration 1:10 water for injections.

Milk “Let-Down”:
• Cow and Mare: 1-4 ml.
• Ewe and Goat: 0,5-2 ml.
• Bitch and Queen: 0,1-1 ml.
WITHDRAWAL PERIOD
- Meat: 1 day.
- Milk: 1 day.